BDBM50055660 1-amino-3-(4-(4-(2-(amino(iminio)methylamino)acetamido)-1-methyl-1H-pyrrole-2-carboxamido)-1-methyl-1H-pyrrole-2-carboxamido)propan-1-iminium::2N-(3-amino-3-iminopropyl)-4-[4-amino(imino)methylaminomethylcarboxamido-1-methyl-1H-2-pyrrolylcarboxamido]-1-methyl-1H-2-pyrrolecarboxamide::2N-(3-amino-3-iminopropyl)-4-[4-amino(imino)methylaminomethylcarboxamido-1-methyl-1H-2-pyrrolylcarboxamido]-1-methyl-1H-2-pyrrolecarboxamide(netropsin)::4-(2-Guanidino-acetylamino)-1-methyl-1H-pyrrole-2-carboxylic acid [5-(2-carbamimidoyl-ethylcarbamoyl)-1-methyl-2,3-dihydro-1H-pyrrol-3-yl]-amide::CHEMBL307767::NETROPSIN

SMILES [#6]-n1cc(-[#7]-[#6](=O)-c2cc(-[#7]-[#6](=O)-[#6]\[#7]=[#6](\[#7])-[#7])cn2-[#6])cc1-[#6](=O)-[#7]-[#6]-[#6]-[#6](-[#7])=[#7]

InChI Key InChIKey=KKYDQZNQUMKWPG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50055660   

TargetDNA helicase [35-727](malaria parasite P. falciparum)
International Centre For Genetic Engineering and Biotechnology

LigandPNGBDBM50055660(CHEMBL307767 | 2N-(3-amino-3-iminopropyl)-4-[4-ami...)
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
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TargetDNA helicase [35-727](malaria parasite P. falciparum)
International Centre For Genetic Engineering and Biotechnology

LigandPNGBDBM50055660(CHEMBL307767 | 2N-(3-amino-3-iminopropyl)-4-[4-ami...)
Affinity DataIC50: 4.70E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPlasminogen(Human)
Medical University

LigandPNGBDBM50055660(CHEMBL307767 | 2N-(3-amino-3-iminopropyl)-4-[4-ami...)
Affinity DataIC50: 4.00E+4nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Medical University

LigandPNGBDBM50055660(CHEMBL307767 | 2N-(3-amino-3-iminopropyl)-4-[4-ami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Quantities of 0.2 mL of examined preparation (as control, 0.15 M NaCl), buffer, and 0.1 mL of enzyme solution were mixed together. The mixture was in...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDNA topoisomerase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50055660(CHEMBL307767 | 2N-(3-amino-3-iminopropyl)-4-[4-ami...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibit supercoil relaxation property of topoisomerase I.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed