BDBM50179011 CHEMBL380456::Moracin P

SMILES CC1(C)Oc2cc3oc(cc3cc2CC1O)-c1cc(O)cc(O)c1

InChI Key InChIKey=QFUCSEIKNTUPPA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50179011   

TargetPolyphenol oxidase 2(White button mushroom)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of HIF-1alpha in human Hep3B cells cotransfected with pGL3-HRE-luciferase plasmid after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of HIF-1alpha in human Hep3B cells assessed as decrease in VEGF level after 20 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity protein phosphatase 3(Human)
Korea Research Institute of Bioscience and Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of VHR DS-PTPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Korea Research Institute of Bioscience and Biotechnology (Kribb)

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 10.7nMAssay Description:Inhibition of hypoxia-induced HIF1alpha activation in human Hep3B cells after 16 hrs by HRE-luciferase reporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50179011(Moracin P | CHEMBL380456)
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed