BDBM50046201 (2E)-2-((2E)-2-{[(E)-amino(imino)methyl]hydrazono}-1-methylethylidene)hydrazinecarboximidamide::(2E)-2-((2E)-2-{[(Z)-amino(imino)methyl]hydrazono}-1-methylethylidene)hydrazinecarboximidamide::CHEMBL216913::Methylglyoxalbis(guanylhydrazone)::Mitoguazone::N''-{2-[(diaminomethylene)hydrazono]-1-methylethylidene}carbonohydrazonic diamide::methylglyoxalbisguanylhydrazone

SMILES [#6]-[#6](-[#6]=[#7]-[#7]-[#6](-[#7])=[#7])=[#7]\[#7]=[#6](\[#7])-[#7]

InChI Key InChIKey=AIKZMLJQODKWDJ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50046201   

LigandPNGBDBM50046201(Mitoguazone | (2E)-2-((2E)-2-{[(E)-amino(imino)met...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration of compound against S-Adenosyl-methionine decarboxylase (SAMDC) from rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50046201(Mitoguazone | (2E)-2-((2E)-2-{[(E)-amino(imino)met...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of Diamine oxidase (DAO) from rat small intestine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50046201(Mitoguazone | (2E)-2-((2E)-2-{[(E)-amino(imino)met...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of rat liver form of S-adenosyl-methionine decarboxylase enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed