BDBM50103203 3-(3-Hydroxy-4-methoxy-phenyl)-thieno[2,3-b]pyrrolizin-8-one::3-(3-hydroxy-4-methoxyphenyl)-8H-thieno[2,3-b]pyrrolizin-8-one::CHEMBL287508::MR-22388::Thienopyrrolizine derivative, 4g

SMILES COc1ccc(cc1O)-c1csc2C(=O)c3cccn3-c12

InChI Key InChIKey=IXGRUAKWRHZSAP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50103203   

TargetGlycogen synthase kinase-3 beta(Human)
UniversitÉ

LigandPNGBDBM50103203(MR-22388 | 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno...)
Affinity DataIC50: 1.50E+3nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
UniversitÉ

LigandPNGBDBM50103203(MR-22388 | 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno...)
Affinity DataIC50: 5.50E+3nMAssay Description:Kinase activities were assayed according to the methodology developed by the Cell Cycle Group of the Station Biologique (CNRS).More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
UniversitÉ

LigandPNGBDBM50103203(MR-22388 | 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50103203(MR-22388 | 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CDK1/cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSimilar to alpha-tubulin isoform 1(Bovine)
University of Caen Normandy

Curated by ChEMBL
LigandPNGBDBM50103203(MR-22388 | 3-(3-hydroxy-4-methoxyphenyl)-8H-thieno...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory concentration against calf tubulin polymerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed