BDBM50318402 (Z)-2-(pyridin-3-ylmethylene)-3-(4-(trifluoromethoxy)phenyl)-2,3-dihydro-1H-pyrrolizin-1-one::CHEMBL1095413::MR-16089

SMILES FC(F)(F)Oc1ccc(cc1)C1\C(=C\c2cccnc2)C(=O)c2cccn12

InChI Key InChIKey=NUADOLYUKJMRKY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50318402   

TargetAromatase(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50318402((Z)-2-(pyridin-3-ylmethylene)-3-(4-(trifluorometho...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAromatase(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50318402((Z)-2-(pyridin-3-ylmethylene)-3-(4-(trifluorometho...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed