BDBM50366377 CHEMBL334721::MEN-10627

SMILES CSCC[C@@H]1NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CNC(=O)C[C@H](NC1=O)C(=O)N[C@@H](Cc1c[nH]c3ccccc13)C(=O)N[C@@H](Cc1ccccc1)C(=O)N2

InChI Key InChIKey=CFDNUNSOUUFTQO-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50366377   

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50366377(MEN-10627 | CHEMBL334721)
Affinity DataIC50: 0.0790nMAssay Description:Tested for binding affinity of compound against [125I]NKA binding to neurokinin-2 (NK-2) receptor in hamster urinary bladderMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSubstance-K receptor(Golden hamster)
TBA

Curated by ChEMBL
LigandPNGBDBM50366377(MEN-10627 | CHEMBL334721)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards Tachykinin receptor 2 using [125I]iodohistidyl-NKA (0.1 nM)) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50366377(MEN-10627 | CHEMBL334721)
Affinity DataIC50: 800nMAssay Description:Tested for binding affinity against [125I]BH-SP binding to neurokinin-1 (NK-1) receptor in human IM-9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSubstance-K receptor(Human)
Menarini Ricerche

Curated by ChEMBL
LigandPNGBDBM50366377(MEN-10627 | CHEMBL334721)
Affinity DataKi:  0.631nMAssay Description:Binding affinity towards Tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed