BDBM50204458 CHEMBL245049::MCL-433

SMILES CNC(=O)Oc1ccc2CC3C4CCCCC4(CCN3C)c2c1

InChI Key InChIKey=YJGQAUOQIDQXIT-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50204458   

TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50204458(MCL-433 | CHEMBL245049)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50204458(MCL-433 | CHEMBL245049)
Affinity DataEC50:  29nMAssay Description:Agonist activity at huma kappa opioid receptor expressed in CHO cells assessed as U50488-stimulated of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50204458(MCL-433 | CHEMBL245049)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50204458(MCL-433 | CHEMBL245049)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50204458(MCL-433 | CHEMBL245049)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed