BDBM50095765 1-(2,3,4-trimethoxybenzyl)-4-(bis(4-fluorophenyl)methyl)piperazine::1-[Bis-(4-fluoro-phenyl)-methyl]-4-(2,3,4-trimethoxy-benzyl)-piperazine(Lomerizine)::CHEMBL29188::Lomerizine

SMILES COc1ccc(CN2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)c(OC)c1OC

InChI Key InChIKey=JQSAYKKFZOSZGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50095765   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Ionix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50095765(1-[Bis-(4-fluoro-phenyl)-methyl]-4-(2,3,4-trimetho...)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of calcium channel Cav2.2 in IMR32 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50095765(1-[Bis-(4-fluoro-phenyl)-methyl]-4-(2,3,4-trimetho...)
Affinity DataIC50: 90nMAssay Description:Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed