BDBM50259889 Lodoxamide

SMILES c1c(cc(c(c1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N

InChI Key InChIKey=RVGLGHVJXCETIO-UHFFFAOYSA-N

Data  4 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50259889   

TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50259889(Lodoxamide)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at human GPR35 expressed in CHO-K1 cells after 90 mins by beta-arrestin 2 recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50259889(Lodoxamide)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human GPR35 expressed in HEK293 cells co-expressing Galpha16 assessed as increase in calcium mobilization by Fluo-4 AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetG-protein coupled receptor 35(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50259889(Lodoxamide)
Affinity DataEC50:  422nMAssay Description:Agonist activity at mouse GPR35 expressed in HEK293 cells co-expressing Galpha16 assessed as increase in calcium mobilization by Fluo-4 AM dye based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50259889(Lodoxamide)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human GPR35 by beta-arrestin recruitment assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)