BDBM50587737 LEQ-506::LEQ506::Leq 506::Leq506::NVP-LEQ506::Nvp-leq-506

SMILES C[C@@H]1CN(CCN1c1cnc(cn1)C(C)(C)O)c1nnc(Cc2ccccc2)c(C)c1C

InChI Key InChIKey=POERAARDVFVDLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587737   

TargetSmoothened homolog(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50587737(Leq 506 | Leq506 | Nvp-leq-506 | LEQ-506 | LEQ506 ...)
Affinity DataIC50: 96nMAssay Description:Antagonist activity at resistant Smo D473H mutant (unknown origin) expressed in mouse C3H 10T1/2 cells cotransfected with Gli reporter gene assessed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed