BDBM50294038 CHEMBL116734::LY-329146::N-(4-(6-hydroxy-3-(4-(2-(piperidin-1-yl)ethoxy)benzoyl)benzo[b]thiophen-2-yl)phenyl)-N-(methylsulfonyl)methanesulfonamide::N-(4-{3-[4-(2-hexahydro-1-pyridinylethoxy)benzoyl]-6-hydroxybenzo[b]thiophen-2-yl}phenyl)N,N-dimethanesulfonamide

SMILES CS(=O)(=O)N(c1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1)S(C)(=O)=O

InChI Key InChIKey=RSJYPIKEOWEIPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294038   

TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50294038(LY-329146 | N-(4-{3-[4-(2-hexahydro-1-pyridinyleth...)
Affinity DataIC50: 800nMAssay Description:Inhibition of MRP1-mediated transport of [3H]LTC4 expressed in human HeLa T5 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50294038(LY-329146 | N-(4-{3-[4-(2-hexahydro-1-pyridinyleth...)
Affinity DataIC50: 800nMAssay Description:TP_TRANSPORTER: inhibition of LTC4 uptake (LTC4: 0.5 uM) in membrane vesicles from HL60/ADR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed