BDBM24941 (2Z)-2-{[(2,5-dibromophenyl)amino](hydroxy)methylidene}-3-oxobutanenitrile::CHEMBL228043::LFM-A13::Thr1 inhibitor, 2::alpha-cyano-beta-hydroxy-beta-methyl-N-(2,5-dibromophenyl)propenamide
SMILES CC(=O)C(C#N)C(=O)Nc1cc(Br)ccc1Br
InChI Key InChIKey=BQLDGDMKDYAGNE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 24941
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Purified Plx1 was first incubated with different concentrations of LFM-A13. The substrate, GST-Cdc25 peptide (254-316) and [gamma-32P]ATP were added ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.67E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.81E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 2.15E+5nMAssay Description:The specificity of LFM-A13 was further examined against a broad panel of serine-threonine kinases and tyrosine kinases using the KinaseProfiler Assay...More data for this Ligand-Target Pair
Affinity DataIC50: 1.72E+4nMAssay Description:Inhibition of human BTKMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant BTKMore data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of Plk3More data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of BTKMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant BTK expressed in baculovirus expression vector systemMore data for this Ligand-Target Pair
Affinity DataKi: 7.20E+3nM ΔG°: -6.94kcal/mole IC50: 6.10E+4nMpH: 7.0 T: 2°CAssay Description:The mode of human PLK3 inhibition by LFM-A13 was examined in titration experiments using increasing concentrations of [gamma-32P]ATP and purified N-t...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nM ΔG°: -6.98kcal/molepH: 7.5 T: 2°CAssay Description:The phosphorylation of L-Hse was monitored by coupling the formation of ADP with pyruvate kinase and lactate dehydrogenase (PK/LDH). The resulting o...More data for this Ligand-Target Pair