BDBM50198715 (2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)propanoic acid::CHEMBL245416::L-mimosine

SMILES N[C@@H](Cn1ccc(=O)c(O)c1)C(O)=O

InChI Key InChIKey=WZNJWVWKTVETCG-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50198715   

TargetTyrosinase(Human)
University of Karachi

LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataIC50: 3.68E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 1(White button mushroom)
Yonsei University

LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataIC50: 3.68E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of mushroom tyrosinase after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of mashroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Central University of Las Villas

Curated by ChEMBL
LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase assessed as decrease in L-DOPA chrome formation using L-DOPA as substrate preincubated with...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDeoxyhypusine hydroxylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of DOHH (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosinase(Human)
University of Karachi

LigandPNGBDBM50198715(CHEMBL245416 | L-mimosine | (2S)-2-amino-3-(3-hydr...)
Affinity DataKi:  1.03E+4nMAssay Description:Competitive inhibition of recombinant human tyrosinase expressed in baculovirus infected sf9 cells using L-DOPA as substrate by double-reciprocal plo...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed