BDBM50422052 CHEMBL109952::L-700417

SMILES OC(C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12)C[C@@H](Cc1ccccc1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12

InChI Key InChIKey=NNOFYWJFSHHUJW-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50422052   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50422052(L-700417 | CHEMBL109952)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of HIV-1 protease was determined in vitroMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50422052(L-700417 | CHEMBL109952)
Affinity DataIC50: 0.690nMAssay Description:Inhibitory activity against HIV-1 protease.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50422052(L-700417 | CHEMBL109952)
Affinity DataKd:  0.708nMAssay Description:Affinity for HIV ProteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtease(Human immunodeficiency virus type 1)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50422052(L-700417 | CHEMBL109952)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGag-Pol polyprotein [489-587,G537V,H558K,V571A](Human immunodeficiency virus)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50422052(L-700417 | CHEMBL109952)
Affinity DataKi:  0.370nMAssay Description:Inhibition of recombinant HIV protease expressed in inclusion bodies of Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed