BDBM50148175 CHEMBL114695::KYS-05001::N-Benzyl-2-(3-phenyl-2-piperidin-1-yl-3,4-dihydro-quinazolin-4-yl)-acetamide::N-benzyl-2-(3-phenyl-2-(piperidin-1-yl)-3,4-dihydroquinazolin-4-yl)acetamide

SMILES O=C(CC1N(C(=Nc2ccccc12)N1CCCCC1)c1ccccc1)NCc1ccccc1

InChI Key InChIKey=IROXHJVGJHVBSD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148175   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148175(N-Benzyl-2-(3-phenyl-2-piperidin-1-yl-3,4-dihydro-...)
Affinity DataIC50: 900nMAssay Description:Concentration of the compounds required for inhibition of HEK293 cells (alpha1G T-type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148175(N-Benzyl-2-(3-phenyl-2-piperidin-1-yl-3,4-dihydro-...)
Affinity DataIC50: 900nMAssay Description:Inhibition of alpha-1G T-type calcium channel expressed in HEK293 cells by electrophysiological methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148175(N-Benzyl-2-(3-phenyl-2-piperidin-1-yl-3,4-dihydro-...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of T-type calcium channel Cav3.1 alpha-1G subunit expressed in HEK293 cells assessed as calcium current by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50148175(N-Benzyl-2-(3-phenyl-2-piperidin-1-yl-3,4-dihydro-...)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of T-type [Ca2+] channel (alpha1G) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed