BDBM50431630 KRX-0401::PERIFOSINE

SMILES CCCCCCCCCCCCCCCCCCOP([O-])(=O)OC1CC[N+](C)(C)CC1

InChI Key InChIKey=SZFPYBIJACMNJV-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50431630   

TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 4.34E+4nMAssay Description:Inhibition of human Akt1 PH domain using AKTide-2T as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Akt phosphorylation in human insulin-stimulated A549 cells incubated for 2 hrs prior to insulin-induction measured after 30 mins by ELI...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of wild-type human P38alpha MAPK expressed in Escherichia coli Rosetta cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Human)
University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 50nMAssay Description:Inhibition of UCHL3 (unknown origin) assessed as reduction in RAD51 deubiquitination incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC15 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC2429 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC4017 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC515 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC827 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H2009 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H1993 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H2882 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human NCI-H1819 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetTelomerase reverse transcriptase(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50: 184nMAssay Description:Inhibition of telomerase activity in human HCC38 cells by droplet-digital TRAP PCR assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed