BDBM50196469 3-(3-fluorobenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide::CHEMBL223331::KKHT-10608

SMILES Fc1cccc(Cn2c(=O)[nH]c3cc(ccc3c2=O)C(=O)NCCN2CCCCC2)c1

InChI Key InChIKey=YKQRXGQZAGVEJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50196469   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50196469(3-(3-fluorobenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl)...)
Affinity DataIC50: 1.69E+4nMAssay Description:Inhibition of T-type calcium channel Cav3.1 with alpha-1G subunit by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50196469(3-(3-fluorobenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl)...)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at 5HT3A receptor expressed in Xenopus oocyteMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50196469(3-(3-fluorobenzyl)-2,4-dioxo-N-(2-(piperidin-1-yl)...)
Affinity DataIC50: 1.69E+4nMAssay Description:Antagonist activity against T-type calcium channel alpha1GMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed