BDBM50249783 10-(6-(diethylamino)hexyl)acridin-9(10H)-one::CHEMBL491889::KF-A6

SMILES CCN(CC)CCCCCCn1c2ccccc2c(=O)c2ccccc12

InChI Key InChIKey=YHXSELHUXJAOLR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249783   

TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed