BDBM50249759 10-(2-(diethylamino)ethyl)acridin-9(10H)-one::CHEMBL444412::KF-A2

SMILES CCN(CC)CCn1c2ccccc2c(=O)c2ccccc12

InChI Key InChIKey=RINBNPPEMJIWTC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50249759   

TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(KF-A2 | 10-(2-(diethylamino)ethyl)acridin-9(10H)-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(KF-A2 | 10-(2-(diethylamino)ethyl)acridin-9(10H)-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(KF-A2 | 10-(2-(diethylamino)ethyl)acridin-9(10H)-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed