BDBM50240936 2-[(2E,6E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,6-dienyl]-benzene-1,4-diol::CHEMBL425166::JASPAQUINOL::jasplaquinol

SMILES C\C(CC\C=C(/C)CCC1=C(C)CCCC1(C)C)=C/Cc1cc(O)ccc1O

InChI Key InChIKey=KUTRNQZRJBENDY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50240936   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(CHEMBL425166 | jasplaquinol | 2-[(2E,6E)-3,7-Dimet...)
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(CHEMBL425166 | jasplaquinol | 2-[(2E,6E)-3,7-Dimet...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human platelet N-terminal His6-tagged 12-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(CHEMBL425166 | jasplaquinol | 2-[(2E,6E)-3,7-Dimet...)
Affinity DataIC50: 450nMAssay Description:Inhibition of human N-terminal His6-tagged 5-lipoxygenase arachidonic acid by UV-vis spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California Santa Cruz

Curated by ChEMBL
LigandPNGBDBM50240936(CHEMBL425166 | jasplaquinol | 2-[(2E,6E)-3,7-Dimet...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human reticulocyte N-terminal His6-tagged 15-lipoxygenase by UV-vis spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed