BDBM50098543 10% Sodium Chloride Injection::Broncho Saline::CHEBI:26710::Isotonic::Sodium Chloride::Sodium Chloride Solution::Sodium Chloride, Hypertonic::Table Salt

SMILES [Na+]

InChI Key InChIKey=FKNQFGJONOIPTF-UHFFFAOYSA-N

Data  14 KI

PDB links: 12021 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50098543   

TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi: >2.00E+8nMAssay Description:Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Istituto Di Bioscienze E Biorisorse (Ibbr)-Cnr

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi: >1.00E+8nMpH: 8.3Assay Description:Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi: >2.00E+8nMAssay Description:Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Istituto Di Bioscienze E Biorisorse (Ibbr)-Cnr

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  6.00E+6nMAssay Description:Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Istituto Di Bioscienze E Biorisorse

Curated by ChEMBL
LigandPNGBDBM50098543(CHEBI:26710 | 10% Sodium Chloride Injection | Bron...)
Affinity DataKi:  2.00E+8nMAssay Description:Inhibition of human carbonic anhydrase-2 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)