BDBM50001942 CHEMBL2113668::Iodo-MLA

SMILES [H][C@]12C[C@]3([H])[C@]([H])([C@H]1OC)[C@](O)(C[C@@H]2OC)[C@]1(O)[C@@H](OC)[C@@]2([H])[C@@]33[C@H](CC[C@@]2(COC(=O)c2cc([125I])ccc2N2C(=O)C[C@H](C)C2=O)CN(CC)[C@@]13[H])OC

InChI Key InChIKey=YMDRDNRMRZWDNG-NXJYMPRYSA-N

Data  6 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50001942   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKd:  2nMAssay Description:Dissociation constant for rat Nicotinic acetylcholine receptor alpha-7 at 45 pMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  1.90nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of alpha-bungarotoxinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  3.20nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of methylcaconitine.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  13nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of 3-cinnamylidene-anabasineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  667nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of (-)-nicotineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of dihydro-beta-erythroidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of mecamylamineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed