BDBM50023867 Indirubin

SMILES Oc1[nH]c2ccccc2c1C1=Nc2ccccc2C1=O

InChI Key InChIKey=JNLNPCNGMHKCKO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50023867   

TargetCyclin-dependent kinase 1(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Cyclin-dependent kinase 2 (CDK2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50023867(Indirubin)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed