BDBM50456401 IRIGENOL

SMILES Oc1cc(cc(O)c1O)-c1coc2cc(O)c(O)c(O)c2c1=O

InChI Key InChIKey=DFURNQJNFBMYHM-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50456401   

TargetRegulator of G-protein signaling 17(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of RGS17 (unknown origin) GAP activity in presence of GTP by malachite green dye based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRegulator of G-protein signaling 17(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50: 4.72E+4nMAssay Description:Inhibition of wild type GST-tagged RGS17 (unknown origin) interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRegulator of G-protein signaling 17(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50: 8.18E+4nMAssay Description:Inhibition of RGS17 (unknown origin) C117A mutant interaction with biotinylated Galphao after 30 mins in presence of AMF and GDP by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetRegulator of G-protein signaling 17(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataKd:  7.10E+5nMAssay Description:Binding affinity to RGS17 (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase S(Human)
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50456401(IRIGENOL)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed