BDBM50100712 2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane::CHEMBL54586::Epibatidine-I,(+/-)::IPH

SMILES Ic1ccc(cn1)C1CC2CCC1N2

InChI Key InChIKey=HFZMLKBIAFLYRM-UHFFFAOYSA-N

Data  17 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50100712   

TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.0200nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.0250nMAssay Description:In vitro binding affinity towards (alpha-4)2(beta-2)3 neuronal nicotinic acetylcholine receptor in P2 membrane fractions of rat forebrainMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.0700nMAssay Description:Inhibition of [3H]epibatidine binding at the nicotinic acetylcholine receptor alpha4-beta2 in male rat cerebral cortexMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.0700nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.0700nMAssay Description:Inhibition of [3H]epibatidine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
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TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
Georgetown University

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.110nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.110nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
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TargetNeuronal acetylcholine receptor subunit alpha-2(Rat)
Georgetown University

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
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TargetNeuronal acetylcholine receptor subunit alpha-4(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
Copy reaction URL

TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.180nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNicotinic acetylcholine receptor(Cape York rat)
Georgetown University

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.330nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.480nMAssay Description:Non-specific binding in presence of 300 uM nicotine at nicotinic acetylcholine receptor alpha4-beta2 in rat cerebral cortex membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Institut F£R Pharmazeutische Chemie Der Philipps-Universit£T Marburg

Curated by ChEMBL

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.480nMAssay Description:Inhibition of [125I]-analogue binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranesMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
Copy reaction URL

TargetNeuronal acetylcholine receptor subunit alpha-3(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  0.980nMMore data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetNeuronal acetylcholine receptor subunit alpha-9(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  6.5nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
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TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
National Institute On Drug Abuse

Curated by PDSP K_i Database

LigandBDBM50100712(IPH | Epibatidine-I,(+/-) | CHEMBL54586 | 2-(6-Iod...)Copy SMILESCopy InChI

Affinity DataKi:  30nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
Copy reaction URL