BDBM205001 I-86

SMILES C[C@@]1(N=C(N)O[C@H](CF)[C@@H]1F)c1cc(NC(=O)c2coc(n2)C(F)F)ccc1F

InChI Key InChIKey=WCEJZWFSSCZALB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205001   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM205001(I-86)
Affinity DataIC50: 32.9nMpH: 5.0 T: 2°CAssay Description:48.5 μL of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In DepthDetails
US Patent