BDBM50097041 1-(5-Bromo-pyridin-2-yl)-3-[2-(4-hydroxy-phenyl)-ethyl]-thiourea::CHEMBL144604::HI-244

SMILES Oc1ccc(CCNC(=S)Nc2ccc(Br)cn2)cc1

InChI Key InChIKey=UAUYJJLEWDLTLK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097041   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50097041(1-(5-Bromo-pyridin-2-yl)-3-[2-(4-hydroxy-phenyl)-e...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50097041(1-(5-Bromo-pyridin-2-yl)-3-[2-(4-hydroxy-phenyl)-e...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against non-nucleoside reverse transcriptase inhibitors (NNRTI) -resistant HIV-1 strain A17 with a Y181C mutation in RT (reverse ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLeukotriene C4 synthase(Human)
Zhejiang Sci-Tech University

Curated by ChEMBL
LigandPNGBDBM50097041(1-(5-Bromo-pyridin-2-yl)-3-[2-(4-hydroxy-phenyl)-e...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of LTC4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed