BDBM50459893 Gelsemine

SMILES [H][C@]12CO[C@]3([H])C[C@@]1([H])[C@@]1(CN(C)[C@@]2([H])[C@]1([H])[C@@]31C(=O)Nc2ccccc12)C=C

InChI Key InChIKey=NFYYATWFXNPTRM-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50459893   

TargetGlycine receptor subunit alpha-1/beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50459893(Gelsemine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human glycine receptor alpha1beta expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-2/beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50459893(Gelsemine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human glycine receptor alpha2beta expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50459893(Gelsemine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human glycine receptor alpha3beta expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycine receptor subunit alpha-1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50459893(Gelsemine)
Affinity DataEC50:  590nMAssay Description:Positive allosteric modulation of recombinant human glycine receptor alpha1 expressed in HEK293 cells assessed as increase in glycine-induced current...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed