BDBM85154 2,3,4,5-Tetrahydro-3-(1H-indazole-3-ylmethyl)-N-(4-methoxyphenyl)-N-(1-methylethyl)-2,4-dioxo-5-phenyl-1H-1,5-benzodiazepine-1-acetamide::CCK-A Agonist 1::GW 5823::GW-5823::N-Isopropyl-N-(4-methoxyphenyl)-3-(1H-indazol-3-ylmethyl)-5-phenyl-2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-1-acetamide

SMILES COc1ccc(cc1)N(C(C)C)C(=O)CN1c2ccccc2N(c2ccccc2)C(=O)C(Cc2n[nH]c3ccccc23)C1=O

InChI Key InChIKey=LGYKPDHARJMLQN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 85154   

TargetCholecystokinin receptor type A(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM85154(GW 5823 | 2,3,4,5-Tetrahydro-3-(1H-indazole-3-ylme...)
Affinity DataIC50: 23nMAssay Description:Binding affinity against human Cholecystokinin type A receptor by displacement of [125I]CCK-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM85154(GW 5823 | 2,3,4,5-Tetrahydro-3-(1H-indazole-3-ylme...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against human Cholecystokinin type B receptor by displacement of [125I]CCK-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGastrin/cholecystokinin type B receptor(Human)
Glaxo Wellcome Research and Development

Curated by ChEMBL
LigandPNGBDBM85154(GW 5823 | 2,3,4,5-Tetrahydro-3-(1H-indazole-3-ylme...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2012
Entry Details Article
PubMed