BDBM50379653 CHEMBL2013174::GS-9451

SMILES CC[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@H](CN1C(=O)[C@@H](NC(=O)O[C@@H]1C[C@@H]2C[C@@H]2C1)C(C)(C)C)Oc1cc(nc2c(Cl)c(OCCN3CCOCC3)ccc12)-c1csc(NC(C)C)n1)C(O)=O

InChI Key InChIKey=OTXAMWFYPMNDME-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50379653   

TargetMultidrug resistance-associated protein 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50379653(GS-9451 | CHEMBL2013174)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of MRP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50379653(GS-9451 | CHEMBL2013174)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of MRP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50379653(GS-9451 | CHEMBL2013174)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BCRPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed