BDBM50250510 CHEMBL462879::GARCINONE D

SMILES [#6]-[#8]-c1c(-[#8])cc2oc3cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c3c(=O)c2c1-[#6]-[#6]C([#6])([#6])[#8]

InChI Key InChIKey=AGBGZVGRTKDKHL-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50250510   

TargetAromatase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of aromatase in human placental microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNuclear factor NF-kappa-B p105 subunit(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of p50 after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of nuclear factor NF-kappa-B p65 subunit after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSialidase(Clostridium perfringens)
Graduate School of Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50250510(CHEMBL462879 | GARCINONE D)
Affinity DataKi:  3.30E+3nMAssay Description:Competitive inhibition of Clostridium perfringens neuraminidase by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed