BDBM50080264 1N-[21-benzyl-29-[(Z)-ethylidene]-13,14,23-trihydroxy-35-isopropyl-19,32-dimethyl-3,9,20,28,31,34,37,38-octaoxo-33-oxa-2,8,10,19,22,27,30,36-octaazatetracyclo[16.13.6.122,26.011,16]octatriaconta-11(16),12,14-trien-4-yl]-2-methylpropanamide::CHEMBL437538::FR-901277

SMILES C\C=C1/NC(=O)[C@H]2NC(=O)[C@H](CCCNC(=O)Nc3cc(O)c(O)cc3C[C@H](N(C)C(=O)[C@H](Cc3ccccc3)N3[C@H](O)CC[C@H](NC1=O)C3=O)C(=O)N[C@@H](C(C)C)C(=O)O[C@H]2C)NC(=O)C(C)C

InChI Key InChIKey=MHMMGTGXNPFNAJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50080264   

TargetNeutrophil elastase(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080264(FR-901277 | 1N-[21-benzyl-29-[(Z)-ethylidene]-13,1...)
Affinity DataIC50: 180nMAssay Description:Evaluated for the inhibition of Human Leukocyte Elastase (HLE) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Fujisawa Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50080264(FR-901277 | 1N-[21-benzyl-29-[(Z)-ethylidene]-13,1...)
Affinity DataKi:  12nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed