BDBM10620 (S)-3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate::3-((1S)-1-(Dimethylamino)ethyl)phenyl N-ethyl N-methyl carbamate::3-(1-(dimethylamino)ethyl)phenyl ethyl(methyl)carbamate::3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate::CHEMBL636::ENA-713::Ethyl-methyl-carbamic acid 3-((R)-1-dimethylamino-ethyl)-phenyl ester::Ethyl-methyl-carbamic acid 3-((S)-1-dimethylamino-ethyl)-phenyl ester::Ethyl-methyl-carbamic acid 3-(1-dimethylamino-ethyl)-phenyl ester::Exelon::Rivastigmine::Rivastigmine (1)::SDZ-212-713::SDZ-ENA-713
SMILES [H][C@@](C)(N(C)C)c1cccc(OC(=O)N(C)CC)c1
InChI Key InChIKey=XSVMFMHYUFZWBK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 91 hits for monomerid = 10620
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of human recombinant AChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 179nMAssay Description:Inhibition of purified human plasma BuChE preincubated for 30 mins before DTNB substrate addition by spectrophotometric assay based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human erythrocytes BChEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human plasma AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human erythrocytes AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibition of human AChE by Ellmans testMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of BChE in human serum assessed as hydrolysis of butyrylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of human serum recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of equine serum BChE by spectrophotometric-based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.61E+4nMAssay Description:Inhibition of electric eel AChE by spectrophotometric-based Ellman's methodMore data for this Ligand-Target Pair
Affinity DataKoff: 0.0333s-1Assay Description:Pseudo-irreversible inhibition of Torpedo californica AChE using acetylthiocholine as substrate by cornish bowden plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of equine serum BChE using BTC as substrate preincubated for 15 mins followed by substrate addition measured at 1 min intervals by Ellman ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of electric eel AChE using ATC as substrate preincubated for 15 mins followed by substrate addition measured at 1 min intervals by Ellman ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of equine serum BChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+3nMAssay Description:Inhibition of AChE in rat cortex after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of BChE in rat serum after 15 mins by modified Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of human recombinant acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine iodide as substrate preincubated for 90 mins before substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine iodide as substrate preincubated for 90 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 620nMAssay Description:Inhibition of bovine AChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of equine BuChE after 120 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine as substrate after 10 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of equine BChE using after 10 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of acetylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of butyrylcholinesterase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.56E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate incubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of equine serum BChE using butylthiocholine chloride as substrate incubated for 15 mins prior to substrate addition by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of human serum BuchE after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant butyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SERTMore data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of human AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of mouse brain AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of Swiss albino mouse RBC AChE after 30 mins by Ellman methodMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibitory concentration against human plasma ButyrylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.15E+3nMAssay Description:Inhibitory concentration against human erythrocyte AcetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:In vitro inhibitory concentration against butyrylcholinesterase was determined using rat serum homogenateMore data for this Ligand-Target Pair
Affinity DataIC50: 1.82E+3nMAssay Description:In vitro inhibitory concentration against rat cortex acetylcholinesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: 301nMAssay Description:Inhibition of human serum recombinant BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The reaction mixture containing phosphate buffer, AChE or BChE and chosen compounds was prepared and intensively stirred. In given times (5, 10, 15, ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.52E+4nMAssay Description:The eight synthesized dialkyl-3-cyanopropylphosphates (3a-h) were dissolved in0.01 M dimethyl sulphoxide and then diluted in demineralized water to 1...More data for this Ligand-Target Pair
Affinity DataIC50: 3.84E+4nMAssay Description:The IC50 values were determined using the spectrophotometric Ellman's method. All of the tested compounds were dissolved in 0.01 M DMSO and then ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.61E+4nMAssay Description:The IC50 values were determined using the spectrophotometric Ellman's method. All of the tested compounds were dissolved in 0.01 M DMSO and then ...More data for this Ligand-Target Pair