BDBM392711 Example 5::US10301291, Compound 10e

SMILES Clc1ccc(cc1Cl)-c1ncc(CC#N)n1-c1ccnc(NC2CCOCC2)n1

InChI Key InChIKey=JLBWDBPHKABVBE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 392711   

TargetMitogen-activated protein kinase 10(Human)
Samjin Pharmaceutical

US Patent
LigandPNGBDBM392711(Example 5 | US10301291, Compound 10e)
Affinity DataIC50: 65nMAssay Description:First of all, after a substrate was inserted into a prepared base reaction buffer solution (20 mM Hepes (pH 75), 10 mM MgCl2, 1 mM EGTA, 0.02% Brij35...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetMitogen-activated protein kinase 10(Human)
Samjin Pharmaceutical

US Patent
LigandPNGBDBM392711(Example 5 | US10301291, Compound 10e)
Affinity DataIC50: 290nMAssay Description:Inhibition of human JNK3 incubated for 40 mins in presence of ATP and [gamma33P-ATP] by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails
PubMed