BDBM50036718 4-Phenyl-1,2,3,6-tetrahydro-pyridine::4-phenyl-1,2,3,6-tetrahydropyridine::CHEMBL1901802::CHEMBL6224::EN300-17815

SMILES C1CC(=CCN1)c1ccccc1

InChI Key InChIKey=OMPXTQYWYRWWPH-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50036718   

TargetSigma non-opioid intracellular receptor 1(Human)
New York University

Curated by ChEMBL
LigandPNGBDBM50036718(CHEMBL1901802 | 4-phenyl-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against sigma receptor in bovine cerebellum using 2.0 nM [3H]haloperidol in the presence of 25 nM unlabeled spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
New York University

Curated by ChEMBL
LigandPNGBDBM50036718(CHEMBL1901802 | 4-phenyl-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity against Dopamine receptor D2 in bovine striatal homogenate using 200 pM [3H]- spiperone and 250 nM unlabeled ketanserinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50036718(CHEMBL1901802 | 4-phenyl-1,2,3,6-tetrahydropyridin...)
Affinity DataEC50:  2.45E+3nMAssay Description:Agonist activity at 5HT2C receptor expressed in CHO cells by fluorescence based calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM50036718(CHEMBL1901802 | 4-phenyl-1,2,3,6-tetrahydropyridin...)
Affinity DataIC50: 1.66E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50036718(CHEMBL1901802 | 4-phenyl-1,2,3,6-tetrahydropyridin...)
Affinity DataKi:  7.18E+3nMAssay Description:Displacement of [3H]-mesulergine from 5HT2C receptor expressed in CHO cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed