BDBM50208872 5,6-dimethyl-1H-benzimidazole::5,6-dimethylbenzimidazole::CHEMBL351132::Dimedazol::Dimedazole::Dimesol::Dimezol

SMILES Cc1cc2nc[nH]c2cc1C

InChI Key InChIKey=LJUQGASMPRMWIW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50208872   

TargetCytochrome P450 1A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50208872(5,6-dimethyl-1H-benzimidazole | 5,6-dimethylbenzim...)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of Aryl hydrocarbon hydroxylase in phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Institute of Biological Chemistry and The Genomics Research Center

Curated by ChEMBL
LigandPNGBDBM50208872(5,6-dimethyl-1H-benzimidazole | 5,6-dimethylbenzim...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50208872(5,6-dimethyl-1H-benzimidazole | 5,6-dimethylbenzim...)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of Aminopyrine N-demethylase in Phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50208872(5,6-dimethyl-1H-benzimidazole | 5,6-dimethylbenzim...)
Affinity DataIC50: 9.77E+4nMAssay Description:Inhibition of Aryl hydrocarbon hydroxylase in phenobarbitone-treated ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetCytochrome P450 2B1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50208872(5,6-dimethyl-1H-benzimidazole | 5,6-dimethylbenzim...)
Affinity DataIC50: 1.82E+5nMAssay Description:Inhibitory potency to aminopyrine N-demethylase activity (P450) in hepatic microsomes from phenobarbitone-induced rats.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed