BDBM50491246 Darbufelone

SMILES CC(C)(C)c1cc(\C=C2/SC(N)=NC2=O)cc(c1O)C(C)(C)C

InChI Key InChIKey=AKTXOQVMWSFEBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50491246   

TargetProstaglandin G/H synthase 2(Sheep)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50491246(Darbufelone)
Affinity DataIC50: 480nMAssay Description:Inhibition of sheep placental COX-2 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of stan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50491246(Darbufelone)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of ram seminal vesicle COX-1 using arachidonic acid as substrate assessed as production of PGF2alpha by enzyme immunoassay in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed