BDBM50206006 7,8-Dihydroxy-2H-1-benzopyran-2-one::7,8-dihydroxy-2H-chromen-2-one::7,8-dihydroxycoumarin::CHEMBL244948::Daphnetol

SMILES Oc1ccc2ccc(=O)oc2c1O

InChI Key InChIKey=ATEFPOUAMCWAQS-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50206006   

TargetXanthine dehydrogenase/oxidase(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 3.90E+5nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAutoinducer 2-binding periplasmic protein LuxP(Vibrio harveyi)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer-2-mediated quorum sensing after 3 to 4 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 7.67E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 1.18E+4nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 7.67E+3nMAssay Description:Inhibition of EGFR (unknown origin) using (Glu, Tyr) 4:1 as substrate incubated for [gamma-32P]-ATP incubated for 60 mins by scintillation counter an...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of PKC (unknown origin) using acetylated myelin basic protein (4 to 14 residues) as substrate incubated for [gamma-32P]-ATP incubated for ...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetcAMP-dependent protein kinase catalytic subunit gamma(Human)
Quaid-I-Azam University

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataIC50: 9.33E+3nMAssay Description:Inhibition of PKA (unknown origin) using Kemptide as substrate incubated for [gamma-32P]-ATP incubated for 5 mins by scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50206006(7,8-dihydroxy-2H-chromen-2-one | 7,8-dihydroxycoum...)
Affinity DataKi:  1.75E+3nMAssay Description:Displacement of FAM-Bid peptide from recombinant N-terminal His6x-tagged human Mcl-1 expressed in Escherichia coli BL21 (DE3) incubated for 30 mins b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed