BDBM50048403 1,1'-(Deca-4,6-diyne-1,10-diyl)bis(4-amino-2-methylquinolinium) Diiodide Hydrate::1-[10-(4-amino-2-methyl-1-quinoliniumyl)decyl]-2-methyl-4-quinoliniumamine::1-[10-(4-amino-2-methyl-1-quinoliniumyl)decyl]-2-methyl-4-quinoliniumamine dichloride::1-[10-(4-amino-2-methyl-1-quinoliniumyl)decyl]-2-methyl-4-quinoliniumamine dichloride ; Dequalinium::1-[10-(4-amino-2-methyl-1-quinoliniumyl)decyl]-2-methyl-4-quinoliniumamine(Deq)::1-[10-(4-amino-2-methyl-1-quinoliniumyl)decyl]-2-methyl-4-quinoliniumamine(dequalinium)::CHEMBL121663::DQ+::Dequalinium chloride::Dequqlinium::GNF-Pf-5483::dequalinium

SMILES Cc1cc(=[NH2+])c2ccccc2n1CCCCCCCCCCn1c(C)cc(=[NH2+])c2ccccc12

InChI Key InChIKey=PCSWXVJAIHCTMO-UHFFFAOYSA-P

Data  2 KI  6 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50048403   

LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataKd:  180nMAssay Description:Inhibition of Wistar rat recombinant SK3 channel expressed in HEK293 cells by whole cell patch clamp techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Kca2.3 channel expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 740nMAssay Description:The SKCa-blocking action was assessed by its ability to inhibit the after hyperpolarization (AHP) in cultured rat sympathetic neuronesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 900nMAssay Description:Inhibition of after hyperpolarization (AHP) of cultured rat sympathetic neurons as SKCa channel blocking activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 650nMAssay Description:The blocking of apamin-sensitive [Ca2+]-activated K+ (SKCa) channel was assessed by the compounds ability to inhibit the after-hyperpolarization in c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataIC50: 1.00E+3nMAssay Description:SKCa-blocking activity by its ability to inhibit after hyperpolarization (AHP) in cultured rat sympathetic neuronsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataKi:  140nMAssay Description:Displacement of [I125]apamine from Wistar rat recombinant SK3 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
LigandPNGBDBM50048403(dequalinium | 1-[10-(4-amino-2-methyl-1-quinoliniu...)
Affinity DataKi:  221nMAssay Description:Displacement of [125I]apamin from SK channel in Wistar rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed