BDBM50014989 2-(4-tert-Butyl-2,5-dimethoxy-phenyl)-1-methyl-ethylamine::CHEMBL8317::DOTB

SMILES COc1cc(c(OC)cc1CC(C)N)C(C)(C)C

InChI Key InChIKey=RUAUPNFNQOGIFF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50014989   

Target5-hydroxytryptamine receptor 2C(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50014989(DOTB | CHEMBL8317 | 2-(4-tert-Butyl-2,5-dimethoxy-...)
Affinity DataKi:  2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50014989(DOTB | CHEMBL8317 | 2-(4-tert-Butyl-2,5-dimethoxy-...)
Affinity DataKi:  3.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50014989(DOTB | CHEMBL8317 | 2-(4-tert-Butyl-2,5-dimethoxy-...)
Affinity DataKi:  19nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor of rat frontal cortex using [3H]ketanserin radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50014989(DOTB | CHEMBL8317 | 2-(4-tert-Butyl-2,5-dimethoxy-...)
Affinity DataKi:  24.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50014989(DOTB | CHEMBL8317 | 2-(4-tert-Butyl-2,5-dimethoxy-...)
Affinity DataKi:  49.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed