BDBM50180948 CHEBI:30805::DODECANOATE::Dodecanoic Acid::Dodecanoic Acid Anion::Lauric Acid

SMILES CCCCCCCCCCCC(O)=O

InChI Key InChIKey=POULHZVOKOAJMA-UHFFFAOYSA-N

Data  1 KI  3 IC50  6 EC50

PDB links: 99 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50180948   

TargetFree fatty acid receptor 1(Human)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataEC50:  7.94E+3nMAssay Description:Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataEC50:  759nMAssay Description:Agonist activity at FFA1 receptor (unknown origin) expressed in human 132N1 cells measured for 90 secs by Fura-2 AM dye based calcium mobilization as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2017
Entry Details Article
PubMed
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataEC50:  8.87E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as inhibition of forskolin-stimulat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataEC50:  3.49E+3nMAssay Description:Agonist activity at recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 assessed as beta-arrestin 2 recruitment meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataEC50:  8.80E+3nMAssay Description:Agonist activity at human GPR84 expressed in CHO cells assessed as reduction in forskolin-stimulated cAMP production preincubated for 20 mins followe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at human GPR84 expressed in CHO cell membranes assessed as induction of [35S]GTPgammaS incorporation incubated for 1 hr by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetG-protein coupled receptor 84(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50180948(DODECANOATE | CHEBI:30805 | Dodecanoic Acid | Dode...)
Affinity DataKi:  2.17E+3nMAssay Description:Displacement of [3H]PSB-1584 from recombinant human GPR84 expressed in CHO cell membranes co-expressing beta-arrestin2 measured after 6 hrs by scinti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed