BDBM18961 (2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]phenoxy}ethyl)diethylamine::CHEMBL461546::DDIA::Desdiiodoamiodarone::L 3937

SMILES CCCCc1oc2ccccc2c1C(=O)c1ccc(OCCN(CC)CC)cc1

InChI Key InChIKey=PNZXBMCTFUFPLR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 18961   

TargetThyroid hormone receptor alpha(Chicken)
University of Amsterdam

LigandPNGBDBM18961(DDIA | L 3937 | CHEMBL461546 | (2-{4-[(2-butyl-1-b...)
Affinity DataIC50: 1.62E+5nMpH: 7.6 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Rat)
University of Amsterdam

LigandPNGBDBM18961(DDIA | L 3937 | CHEMBL461546 | (2-{4-[(2-butyl-1-b...)
Affinity DataIC50: 9.10E+4nMpH: 7.6 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRbeta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2007
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM18961(DDIA | L 3937 | CHEMBL461546 | (2-{4-[(2-butyl-1-b...)
Affinity DataEC50:  33nMAssay Description:Antagonist activity at rat TAAR1 expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed