BDBM50275550 2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine::CHEMBL487581::D3RKN_68

SMILES Cc1ccc2c(c(nn2c1)c3ccc(cc3)F)c4ccncc4

InChI Key InChIKey=DLJKUEGEDDMTMQ-UHFFFAOYSA-N

Data  1 IC50  3 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275550   

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50: 150nMAssay Description:Inhibition of GST-fused p38alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetTyrosine-protein kinase JAK2(Human)
D3R/Abbott

LigandPNGBDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetMitogen-activated protein kinase 14(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275550(2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  20nMAssay Description:D3R2023More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R