BDBM50339905 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE::5'-O-[N-(L-cysteinyl)sulfamoyl]adenosine::CHEMBL1163074::CysSA

SMILES N[C@@H](CS)C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=FTSDEWPMACCNGN-UHFFFAOYSA-N

Data  1 KI  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50339905   

TargetL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50339905(CysSA | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE ...)
Affinity DataIC50: 50nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant MBP-tagged MshC assessed as formation of fluorescently labeled Cys-GlcN-Ins by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetL-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50339905(CysSA | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE ...)
Affinity DataKd:  48.5nMAssay Description:Binding affinity to Mycobacterium tuberculosis recombinant MBP-tagged MshC by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetYersiniabactin biosynthetic protein(Yersinia pestis)
Weill Cornell Graduate School of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50339905(CysSA | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE ...)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant Yersinia pestis C-terminal His6-tagged HMWP2 cysteine adenylation domain (1 to 1491 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetYersiniabactin biosynthetic protein(Yersinia pestis)
Weill Cornell Graduate School of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50339905(CysSA | 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE ...)
Affinity DataKi:  240nMAssay Description:Inhibition of recombinant Yersinia pestis C-terminal His6-tagged HMWP2 cysteine adenylation domain (1 to 1491 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed