BDBM50001022 (2S,6S,11S)-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::(SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyclo[9.1.1.0*3,8*]trideca-3(8),4,6-trien-6-ol(cyclazocine)::3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL293349::CYCLAZOCINE (-)::Cyclazocine::Cyclazocine (+)

SMILES C[C@@H]1[C@@H]2Cc3ccc(O)cc3[C@@]1(C)CCN2CC1CC1

InChI Key InChIKey=YQYVFVRQLZMJKJ-UHFFFAOYSA-N

Data  21 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50001022   

TargetMu-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.320nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetDelta-type opioid receptor(Pig)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/9/2012
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  47nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  96nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  111nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  125nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  149nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  365nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  408nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  504nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed
LigandPNGBDBM50001022((SSS)-12-Cyclopropylmethyl-13-methyl-12-aza-tricyc...)
Affinity DataKi:  2.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2011
Entry Details Article
PubMed