BDBM50040929 4,5-dianilinophthalimide::5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione::CHEMBL268868::Cgp 52411

SMILES O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc3ccccc3)cc12

InChI Key InChIKey=AAALVYBICLMAMA-UHFFFAOYSA-N

Data  2 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50040929   

TargetcAMP-dependent protein kinase(Rabbit)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibitory activity was determined against protein kinase A (PKA) of rabbitMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory activity against c-src tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PDGF-dependent autophosphorylation of PDGF-R in mouse BALB/c3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1/ABL2(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against v-abl tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of EGF-dependent autophosphorylation of EGF-R in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 300nMAssay Description:Inhibitory activity against recombinant tyrosine kinase EGF-R (EGF-R ICD)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataIC50: 300nMAssay Description:In vitro inhibitory activity against epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ciba-Geigy

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataKi:  160nMAssay Description:Competitive inhibition of ATP binding to EGF-RMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50040929(5,6-bis(phenylamino)-1H-isoindole-1,3(2H)-dione | ...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I-N-Methyl-4-(4-bromoanilino)phthalimide from beta-amyloid plaques isolated from Alzheimer's disease patient brainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed