BDBM50482777 CHEBI:204928::Cefotaxime

SMILES [H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O

InChI Key InChIKey=GPRBEKHLDVQUJE-UHFFFAOYSA-N

Data  19 IC50

PDB links: 7 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50482777   

TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 7.02E+4nMAssay Description:Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 6(Rat)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 2.00E+6nMAssay Description:TP_TRANSPORTER: inhibition of PAH uptake in OAT1-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSolute carrier family 22 member 8(Rat)
Kyorin University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 8.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of Estrone sulfate uptake in OAT3-expressing S2 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 548nMAssay Description:Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 548nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 219nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 2.19E+3nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 548nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 8.78E+3nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 2527 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 2.81E+5nMAssay Description:Binding affinity to methicillin-resistant, heteroresistant vancomycin-intermediate, beta-lactamase-negative Staphylococcus aureus 873 PBP2a by compet...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 2.19E+3nMAssay Description:Binding affinity to methicillin-, vancomycin-resistant, beta-lactamase-positive Staphylococcus aureus 510 PBP2a by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2x(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 8.78E+3nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP2X by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 548nMAssay Description:Binding affinity to against methicillin-, daptomycin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 25 PBP2a by co...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 2.81E+5nMAssay Description:Binding affinity to methicillin-, linezolid-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 2149A PBP2a by competit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 3.51E+4nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 3413 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 2B(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 3.51E+4nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP2B by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 274nMAssay Description:Binding affinity to penicillin-resistant Streptococcus pneumoniae 24 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPenicillin-binding protein 1A(Streptococcus pneumoniae serotype 4 (strain ATCC B...)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 219nMAssay Description:Binding affinity to against penicillin-susceptible Streptococcus pneumoniae 1076 PBP1A by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: 4.39E+3nMAssay Description:Binding affinity to methicillin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 1287 PBP2a by competitive binding a...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed