BDBM50233086 8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)methyl)-1H-pyrazol-4-yl)-1-propyl-1H-purine-2,6(3H,7H)-dione::CHEMBL252048::CVT-6694

SMILES CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1cnn(Cc2noc(n2)-c2ccc(Cl)cc2)c1

InChI Key InChIKey=HWHLLTUJISZFDN-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50233086   

TargetAdenosine receptor A2b(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]DPCPX to human A2B adenosine receptor derived from HEK cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-ZM241385 from human A2B receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi:  7nMAssay Description:Displacement of 3H-ZM214385 from human Adenosine A2B receptor expressed in HEK293 cells after 90 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2b(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi:  7nMAssay Description:Antagonist activity against human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]ZM241385 from human A2A receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A2a(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi: >5.00E+3nMAssay Description:Antagonist activity against human adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi: >6.00E+3nMAssay Description:Displacement of [3H]-CPX from human A1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A1(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi: >6.00E+3nMAssay Description:Antagonist activity against human adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi: >9.00E+3nMAssay Description:Displacement of [125I]-AB-MECA from human A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAdenosine receptor A3(Human)
Cv Therapeutics

Curated by ChEMBL
LigandPNGBDBM50233086(8-(1-((5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl)met...)
Affinity DataKi: >9.00E+3nMAssay Description:Antagonist activity against human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed