BDBM50054488 CHEMBL138441::CVS-1178::N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-phenylmethanesulfonylamino-piperidin-1-yl)-acetamide

SMILES NC(=N)NCCC[C@H](NC(=O)CN1CCC[C@H](NS(=O)(=O)Cc2ccccc2)C1=O)C=O

InChI Key InChIKey=WZYFZDIYCCGIQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054488   

TargetAnionic trypsin(Bovine)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-...)
Affinity DataIC50: 1.55E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Corvas International

Curated by ChEMBL
LigandPNGBDBM50054488(N-((S)-1-Formyl-4-guanidino-butyl)-2-((S)-2-oxo-3-...)
Affinity DataIC50: 12.4nMAssay Description:Compound was evaluated for inhibition of amidolytic activity for chromogenic substrate thrombin F11a.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed