BDBM92261 CS251

SMILES NC[C@H](NC(=O)c1ccc(cc1)C#Cc1ccccc1)C(=O)NO

InChI Key InChIKey=DAUPXPHTYGUEQU-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92261   

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Aquifex aeolicus (strain VF5))
Csar

LigandPNGBDBM92261(CS251)
Affinity DataKd:  108nMpH: 7.0 T: 2°CAssay Description:ThermofluorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Aquifex aeolicus (strain VF5))
Csar

LigandPNGBDBM92261(CS251)
Affinity DataKd:  2.67E+3nMpH: 7.0 T: 2°CAssay Description:ITCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
D3R/Abbott

LigandPNGBDBM92261(CS251)
Affinity DataKd:  108nMAssay Description:Thermofluor_Method1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R

TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Escherichia coli (strain K12))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM92261(CS251)
Affinity DataIC50: 15nMAssay Description:Inhibition of Escherichia coli str. K-12 substr. MG1655 LpxC using UDP-3-O-(R-3-hydroxydecanoyl)-N-acetylglucosamine as substrate preincubated for 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetUDP-3-O-acyl-N-acetylglucosamine deacetylase(Aquifex aeolicus (strain VF5))
Csar

LigandPNGBDBM92261(CS251)
Affinity DataKi:  10nM ΔG°:  -10.9kcal/molepH: 7.0 T: 2°CAssay Description:OctetRedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details PubMed